Atlas of Gastroenterological Endoscopy
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Granular cell tumor
Granular cell tumor In the lower section of the picture a minute polypoid, yellowish tumor is shown. Histology reveals a granular cell tumor. The tumors are thought to originate from Schwann- cells. The tumor is mostly benign, but also shows malignant behaviour in very rare cases. It makes up 0,5-5% of all benign esophageal tumors. Histology shows an unstructered pattern of tumor cells with an eosinophilic, granular cytoplasma and a small nucleolus. In immunhistochemic studies antibodies react with vimentin, protein S100 and neuron specific enolase.