Atlas of Gastroenterological Endoscopy
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Melanosis coli caused by laxatives abuse
Melanosis coli 5 years after end of laxative misuse
Both upper pictures and left lower picture: Typical finding of melanosis coli with a dark brown pattern of the mucosa. Both patients had a long history of laxative abuse (anthrachinones). Melanosis coli is associated with an increased incidence of colorectal tumors (recent publication), but is not agreed to be a precancerous lesion. Right upper picture: Five years after cessation of abuse the colonic mucosa is free of brown pigment. This prooves, that melanosis coli is a reversible disease, when the medication is stopped completely.
Melanosis coli Melanosis coli